Perinatoloji Dergisi 2004; 12(4): 173-178
Online published date : 1 March 2005

Dandy walker malformatıon and varıatıon: prenatal ultrasonographıc features and clınıcal outcome

 
Melih Atahan GÜVEN*, Serdar CEYLANER**, Gülay CEYLANER**
 
*Sütçüimam Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalı, Kahramanmaraş ve **Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi Genetik Merkezi, Ankara.
 

Objective: Our aim was to document cases with Dandy Walker Malformation (DWM) and Dandy Walker Variant (DWV) diagnosed in Kahramanmaras Sütçüimam Üniversity, Faculty of Medicine, Obstetrics Clinic between December 2003 and December 2004.

Materials and Method: In this study covers the patients admitted to the Department of Obstetrics and Gyneacology at KSU Faculty of Medicine during the previous year, in their 12th to 35th gestational weeks for routine ultrasonographic control (low risk group, n:300) and/or those referred due to abnormal ultrasonographic findings (high risk group, n:300). Ultrasonographic images of cases diagnosed prenatally were digitally recorded for postmoprtem and/or neonatal evaluation and comparison. Study is accomplished with detailed postmortem evaluation and gathering neonatal data.

Results: Thirtynine patients (7%) had an anomaly. While 9 anomalies (23%) were detected in the low risk group having routine ultrasonography, the remaining 30 (77%) anomalies were among the high risk group. Cardiac anomalies (n:13, 33%) and neural tube defects (NTD) (n:13, 33%) consist the majority of fetal anomalies while Dandy-Walker malformation and its variant (n:8, 21%) took the third place. The number of Dandy Walker cases were 5 (63%), while DWV cases were 3 (37%). The most frequent inrtacranial and extracranial findings of Dandy Walker cases were agenesis of corpus callosum and cardiac anomalies respectively. Chromosomal evaluations were done in six cases with Dandy Walker cases and 3 of them had chromosomal abnormalities (%50).

Conclusison: Dandy Walker malformation and its variant were the most frequent intracranial malformations detected in cases evaluated in our outpatient clinic. It must be kept in mind that chromosomal anomalies and additional anomalies, especially cardiac, may accompany this malformation.anomalies, especially intracranial, may accompany this malformation.

 
Keywords

Dandy Walker Malformation, Dandy Walken Variant, Ultrasonography, Pregnancy