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Objective: The aim of this study is to evaluate the distribution of the major fetal abnormalities with respect to systems and some related clinical properties during five years period.
Methods: A total number of 55493 deliveries and 56030 neonates were examined retrospectively between 2000-2004. Major fetal defects observed at delivery room were recorded and classified for the distribution of year, system, delivery route, fetal sex, and of prognosis.
Results: Single or multiple fetal abnormalities were identified in 247 cases. The incidence of major abnormality was 0.44 % at the time of delivery. The most common abnormality was that of the central nervous system (54.66%). Two third of these cases had delivered vaginally, one third of them had cesarean section. We revealed that 32% of major anomaly cases dead at the antenatal and very early postnatal period.
Conclusions: The prevalence of major fetal abnormalities was 0.44% and central nervous system abnormalities were the most frequent abnormalities at the deliveries in our clinic. We found that 32% of the cases with major abnormality dead at the antenatal or very early postnatal period. Most deliveries of the babies with major abnormality were done by vaginal route. We suppose that in order to determine realistic major abnormality rates, routine ultrasonographic scanning should be done and nationally oriented detailed records should be documented.
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